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Combining three-MMC with specified substances like Alcoholic beverages or stimulants raises challenges. Taking it with serotonin releasers like copyright or anti-depressants could potentially cause dangerously large serotonin levels.

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three-MMC has two methyl substitutions on its cathinone skeleton, one particular at R3 with the phenyl ring, and also a 2nd with the nitrogen group RN. 3-MMC is analogous to mephedrone; it is actually equivalent in framework count on for the placement of the methyl team at R3 in place of R4.

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